Endocrine Abstracts

Background: Bisphosphonates are capable of suppressing parathormone (PTH)-mediated bone resorption and can be used as an adjunct treatment in acute hypercalcemia. We investigated the effects of oral alendronate on bone mineral density (BMD) and biochemical markers of calcium and bone metabolism in patients with primary hyperparathyroidism (PHPT).Methods: Twenty-six patients aged 58.5±13.9 years with confirmed PHPT were treated with alendronate (70 m...

Results of several clinical studies have suggested that there is an excess risk of cardiovascular disease in persons with vitamin D deficiency.We examined association between serum levels of vitamin D - 25(OH)D and select cardiovascular risk factors in 254 postmenopausal women at a mean age of 55.38±205 years.Vitamin D levels, lipoproteins, TNF-α, Interleukin 6, adiponectin, insulin (using RIA methods) and glucose were as...